Physician Scientist in Clinical Pathology

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portfolio

publications

Methamphetamine and HIV-Tat alter murine cardiac DNA methylation and gene expression

Published in Toxicology and Applied Pharmacology, 2015

Cardiac epigenetic and transcriptional consequences of combined methamphetamine and HIV-Tat exposure.

Recommended citation: Koczor, C. A., Fields, E., Jedrzejczak, M. J., Jiao, Z., Ludaway, T., Russ, R., Shang, J., Torres, R. A., & Lewis, W. (2015). "Methamphetamine and HIV-Tat alter murine cardiac DNA methylation and gene expression." Toxicology and Applied Pharmacology, 288(3), 409–419.
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Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via β-catenin

Published in Nature Cell Biology, 2018

Cytoskeletal regulator CRAD loss drives mucinous colorectal carcinogenesis through β-catenin.

Recommended citation: Jung, Y. S., Wang, W., Jun, S., Zhang, J., Srivastava, M., Kim, M. J., Lien, E. M., Shang, J., Chen, J., McCrea, P. D., Zhang, S., & Park, J. (2018). "Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via β-catenin." Nature Cell Biology, 20(11), 1303–1314.
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Advancing scientific knowledge in times of pandemics

Published in Nature Reviews Immunology, 2020

On rapid peer review and preprint evaluation during a public health emergency.

Recommended citation: Vabret, N., Samstein, R., Fernandez, N., Merad, M., and the Sinai Immunology Review Project (2020). "Advancing scientific knowledge in times of pandemics." Nature Reviews Immunology, 20(6), 338.
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Immunology of COVID-19: Current State of the Science

Published in Immunity, 2020

Comprehensive early synthesis of COVID-19 immunology from the Sinai Immunology Review Project.

Recommended citation: Vabret, N., Britton, G. J., Gruber, C., et al. (2020). "Immunology of COVID-19: Current State of the Science." Immunity, 52(6), 910–941.
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Human microbial transplant restores T cell cytotoxicity and anti-tumor response to PD-L1 blockade in gnotobiotic mice

Published in bioRxiv (preprint), 2020

Gnotobiotic evidence that defined human microbial communities restore checkpoint blockade responsiveness.

Recommended citation: Borgerding, J. N., Shang, J., Britton, G. J., Salmon, H., Bigenwald, C., Maier, B., Rose, S. R., Mogno, I., Kamphorst, A. O., Merad, M., & Faith, J. J. (2020). "Human microbial transplant restores T cell cytotoxicity and anti-tumor response to PD-L1 blockade in gnotobiotic mice." bioRxiv, 2020.08.07.242040.
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SARS-CoV-2 antibody seroconversion in care home

Published in Nature Reviews Immunology, 2020

Preprint Club commentary on antibody seroconversion dynamics in a care home cohort.

Recommended citation: Shang, J., & Moreira, A. (2020). "SARS-CoV-2 antibody seroconversion in care home." Nature Reviews Immunology, 20(11), 649.
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Baseline colitogenicity and acute perturbations of gut microbiota in immunotherapy-related colitis

Published in Journal of Experimental Medicine, 2024

First-author dissertation work showing that the gut microbiota of patients who develop immune checkpoint inhibitor-related colitis is colitogenic at baseline, before therapy begins.

Recommended citation: Shang, J., Del Valle, D. M., Britton, G. J., Mead, K. R., Rajpal, U., Chen-Liaw, A., Mogno, I., Li, Z., Menon, R., Gonzalez-Kozlova, E., Elkrief, A., Peled, J. U., Gonsalves, T. R., Shah, N. J., Postow, M., Colombel, J.-F., Gnjatic, S., Faleck, D. M., & Faith, J. J. (2024). "Baseline colitogenicity and acute perturbations of gut microbiota in immunotherapy-related colitis." Journal of Experimental Medicine, 222(1), e20232079.
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talks

teaching

Teaching experience 1

Undergraduate course, University 1, Department, 2014

This is a description of a teaching experience. You can use markdown like any other post.

Teaching experience 2

Workshop, University 1, Department, 2015

This is a description of a teaching experience. You can use markdown like any other post.